| Napoli | Victor James Osimhen | 26 | 4 | 2 | 1 | 32 | 2582 |
| Inter | Lautaro Javier Martínez | 21 | 6 | 1 | 1 | 38 | 2575 |
| Salernitana | Boulaye Dia | 16 | 5 | 1 | 0 | 33 | 2524 |
| Milan | Rafael Alexandre da Conceição Leão | 15 | 8 | 0 | 0 | 35 | 2432 |
| Atalanta | Ademola Lookman Olajade Alade Aylola Lookman | 13 | 6 | 3 | 0 | 31 | 1735 |
| Milan | Olivier Jonathan Giroud | 13 | 5 | 3 | 0 | 33 | 2148 |
| Spezia | M'Bala Nzola | 13 | 2 | 3 | 1 | 32 | 2744 |
| Torino | Arnaldo Antonio Sanabria Ayala | 12 | 4 | 0 | 0 | 33 | 2441 |
| Napoli | Khvicha Kvaratskhelia | 12 | 10 | 2 | 0 | 34 | 2539 |
| Lazio | Ciro Immobile | 12 | 5 | 4 | 1 | 31 | 2228 |
| Roma | Paulo Exequiel Dybala | 12 | 6 | 5 | 0 | 25 | 1750 |
| Sassuolo | Domenico Berardi | 12 | 7 | 7 | 1 | 26 | 1872 |
| Bologna | Riccardo Orsolini | 11 | 4 | 3 | 0 | 32 | 2120 |
| Lazio | Mattia Zaccagni | 10 | 6 | 1 | 0 | 35 | 2783 |
| Udinese | Norberto Bercique Gomes Betuncal | 10 | 1 | 1 | 0 | 33 | 2131 |
| Inter | Romelu Menama Lukaku Bolingoli | 10 | 5 | 2 | 0 | 25 | 1663 |
| Atalanta | Teun Koopmeiners | 10 | 4 | 2 | 2 | 33 | 2860 |
| Juventus | Dušan Vlahović | 10 | 2 | 2 | 1 | 27 | 1930 |
| Bologna | Marko Arnautović | 10 | 0 | 3 | 0 | 21 | 1540 |
| Lazio | Sergej Milinković-Savić | 9 | 8 | 0 | 0 | 36 | 3029 |